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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10889 | CRTh2 antagonist 2 | GPR | |
CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia. | |||
T10084 | CRTh2 antagonist 1 | GPR | |
CRTh2 antagonist 1 is a CRTh2 antagonist (IC50: 89 nM). | |||
T10890 | CRTh2 antagonist 3 | Others | |
CRTh2 antagonist 3 is a powerful chemokine receptor homologous molecule expressed on Th2 cell (CRTh2) antagonists. CRTh2 antagonist 3 enhanced the activity of PDK1 on short peptide substrates with EC50 of 2 μM and Kd of ... | |||
T7359 | CAY10471 Racemate | TM30089 Racemate | GPR , Prostaglandin Receptor |
CAY10471 Racemate (TM30089 Racemate) is a potent, highly selective CRTH2/DP 2 receptor antagonist. CAY10471 Racemate binds to the human CRTH2/DP2, DP1, and TP receptors( Ki values of 0.6, 1200, and >10,000 nM,respectivel... | |||
T14565 | BI-671800 | AP-761,Cmpd A | GPR , Prostaglandin Receptor |
BI-671800 (AP-761) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2). With IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2... | |||
T77601 | (2-{[2-(2-fluorophenoxy)ethyl]sulfanyl}-1H-benzimidazol-1-yl)acetic acid | GPR | |
(2-{[2-(2-fluorophenoxy)ethyl]sulfanyl}-1H-benzimidazol-1-yl)acetic acid is a prostaglandin-like CRTH2 antagonist with an IC50 < 10 μM, which can be used in studies of rhinitis, COPD, rheumatoid arthritis, eczema and con... | |||
T2396 | Ramatroban | BAY u3405 | GPR , Prostaglandin Receptor , PPAR |
Ramatroban (BAY u3405) (BAY u3405) is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis. It has been used in trials studying the treatment of Asthma. |